A Decade of IPS Cell Research in ALS

09 Nov 2019
14:45 - 15:30

A Decade of IPS Cell Research in ALS

It has now been roughly 10 years since we first reported production of the first motor neurons derived from patients with ALS. In the subsequent decade, methods for using these cells have ever improved, now allowing us to produce preparation of disease-relevant cells from large numbers of individuals. I will relate progress we have made in using these models to study the heterogeneity of ALS, to understand the mechanisms leading to neural degeneration, identify new biomarkers and nominate novel therapeutic targets.